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High-Strength Fish Oil with Sea Buckthorn Seed Oil and Garlic Oil:
An Evidence-Based Combination for Heart, Brain and Overall Wellness

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Modern lifestyles, unbalanced diets, and chronic stress can negatively affect cardiovascular and metabolic health. A combination of high-strength fish oil (700 mg EPA + 350 mg DHA) together with sea buckthorn seed oil and garlic oil provides multiple bioactive compounds that have been studied for their potential to support heart, brain, eye, and overall health.

Below is a review of the clinical evidence behind each ingredient.

10 July, 2026

Key Takeaways

  • 700 mg EPA + 350 mg DHA provides 1,050 mg of omega-3 fatty acids (EPA+DHA), a dosage commonly studied in clinical research.

  • EPA and DHA support heart, brain, and eye health.

  • Fish oil helps maintain healthy triglyceride levels.

  • Sea buckthorn seed oil provides antioxidants and supports skin and vascular health.

  • Garlic oil contains sulfur compounds that support healthy circulation and cardiovascular wellness.

  • Together, these ingredients provide complementary nutritional support for healthy aging.

What Is High-Strength Fish Oil?

 

High-strength fish oil contains concentrated amounts of the two biologically active omega-3 fatty acids:

  • EPA (Eicosapentaenoic Acid) – 700 mg

  • DHA (Docosahexaenoic Acid) – 350 mg

 

Unlike the total fish oil amount listed on a supplement label, EPA and DHA are the key active components responsible for most of the clinically studied health benefits.

 

A serving providing 1,050 mg of combined EPA and DHA is considered a meaningful intake and falls within the range investigated in many cardiovascular and metabolic health studies.

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What Are the Benefits of EPA and DHA?

 

1. Supports Heart Health

 

EPA and DHA support cardiovascular health by helping maintain healthy triglyceride levels, supporting blood vessel function, and promoting overall cardiovascular wellness.

 

Omega-3 fatty acids are among the most extensively studied nutrients for cardiovascular health. Research has shown that EPA and DHA help maintain normal triglyceride levels, support endothelial function (the health of blood vessel linings), and contribute to healthy circulation.

 

The American Heart Association recognizes marine omega-3 fatty acids as an important component of a heart-healthy diet.

 

2. Helps Maintain Healthy Triglyceride Levels

 

EPA and DHA help maintain healthy triglyceride levels, particularly when consumed at clinically studied doses.

 

Multiple systematic reviews and meta-analyses have demonstrated that omega-3 fatty acids reduce fasting triglyceride concentrations, with greater effects generally observed at higher daily intakes.

 

Healthy triglyceride levels are an important part of cardiovascular wellness.

 

3. Supports Healthy Blood Vessel Function

 

EPA and DHA help support healthy blood vessels and normal circulation.

 

Healthy blood vessels expand and contract efficiently, allowing blood to circulate effectively throughout the body.

Studies suggest omega-3 fatty acids support:

  • Healthy endothelial function

  • Normal vascular flexibility

  • Healthy blood flow

  • Nitric oxide production

These effects contribute to overall cardiovascular wellness.

 

4. Supports Brain Function

 

DHA is an important structural component of the brain and supports normal cognitive function.

 

DHA is highly concentrated in brain cell membranes and contributes to normal brain structure and function.

Adequate DHA intake supports:

  • Memory

  • Learning

  • Cognitive performance

  • Healthy brain aging

EPA complements DHA by supporting healthy inflammatory balance.

 

5. Supports Eye Health

 

DHA contributes to the maintenance of normal vision.

 

The retina contains one of the body's highest concentrations of DHA.

Research indicates adequate DHA intake supports:

  • Retinal health

  • Visual function

  • Long-term eye wellness

Some studies also suggest omega-3 fatty acids may support tear production and eye comfort.

What Are the Benefits of Sea Buckthorn Seed Oil?

Sea buckthorn seed oil provides antioxidants, vitamin E, carotenoids, and essential fatty acids that support skin health and help protect cells from oxidative stress.

 

Sea buckthorn seed oil naturally contains:

  • Vitamin E

  • Carotenoids

  • Plant sterols

  • Polyphenols

  • Omega-3

  • Omega-6

  • Omega-9 fatty acids

These nutrients contribute to healthy aging and overall wellness.

 

1. Supports Antioxidant Protection

 

Oxidative stress occurs when free radicals exceed the body's antioxidant defenses.

Sea buckthorn seed oil contains antioxidants that help protect cells from oxidative damage.

 

2. Supports Skin Health

 

Clinical studies suggest sea buckthorn oil may help support:

  • Skin hydration

  • Skin elasticity

  • Skin barrier function

  • Healthy-looking skin

These benefits are attributed to its unique combination of fatty acids and antioxidants.

 

3. Supports Vascular Wellness

 

Emerging research suggests sea buckthorn's antioxidants may help support healthy endothelial function and protect blood vessels from oxidative stress.

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What Are the Benefits of Garlic Oil?

 

Garlic oil contains naturally occurring sulfur compounds that support healthy circulation, antioxidant defenses, and cardiovascular wellness.

 

Garlic has been used traditionally for centuries and has been extensively investigated in modern nutrition research.

Its bioactive compounds include:

  • Diallyl disulfide

  • Diallyl trisulfide

  • Allyl sulfides

 

1. Supports Healthy Circulation

 

Garlic supports normal blood vessel function and healthy circulation through multiple biological pathways.

Research suggests that garlic may help support endothelial function and nitric oxide bioavailability.

 

2. Provides Antioxidant Protection

 

Garlic contains sulfur compounds with antioxidant properties that help reduce oxidative stress.

These compounds help support healthy blood vessels and cellular function.

 

3. Supports Healthy Lipid Metabolism

 

Systematic reviews suggest garlic supplementation may help support healthy cholesterol metabolism as part of a healthy lifestyle.

Results vary depending on the garlic preparation, dosage, and duration of supplementation.

Why Combine Fish Oil, Sea Buckthorn Seed Oil, and Garlic Oil?

These ingredients provide complementary nutritional support.

Ingredient           Key Nutrients                Main Benefits

Fish Oil

EPA, DHA

Sea Buckthorn Seed Oil

Garlic Oil

Vitamin E, carotenoids, polyphenols

Sulfur compounds

Heart, brain, eyes, triglycerides

Skin, antioxidants, vascular support

Circulation, antioxidant support, cardiovascular wellness

Rather than overlapping, each ingredient contributes different bioactive compounds that support multiple aspects of healthy aging and cardiovascular wellness.

Frequently Asked Questions

 

1. Is 700 mg EPA and 350 mg DHA considered a high-strength fish oil?

Yes. A serving providing 1,050 mg of combined EPA and DHA is considered a high-strength omega-3 formulation and is within the range commonly used in clinical research.

 

2. Why are EPA and DHA more important than total fish oil?

The total fish oil amount includes inactive fats. EPA and DHA are the omega-3 fatty acids responsible for most of the clinically studied health benefits.

 

3. Can these ingredients be taken together?

Yes. Fish oil, sea buckthorn seed oil, and garlic oil provide complementary nutrients and are commonly combined in dietary supplements designed to support cardiovascular and overall wellness.

Individuals taking anticoagulant medications or preparing for surgery should consult a healthcare professional before using fish oil or garlic supplements.

 

4. Who may benefit from this combination?

This combination may be suitable for adults who:

  • Consume little oily fish.

  • Want to support heart, brain, and eye health.

  • Wish to increase their intake of omega-3 fatty acids.

  • Are looking for additional antioxidant support as part of a healthy lifestyle.

References

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  1. Calder PC. Omega-3 fatty acids and inflammatory processes. Nutrients. 2010;2(3):355–374.

  2. Skulas-Ray AC, et al. Dose-response effects of omega-3 fatty acids on triglycerides, inflammation, and endothelial function in healthy persons with moderate hypertriglyceridemia. Am J Clin Nutr. 2010  

  3. Abdelhamid AS, et al. Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2020.

  4. Skulas-Ray AC, et al. Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: An American Heart Association Scientific Statement. Circulation. 2019.

  5. Chen Y, et al. Research progress of sea buckthorn (Hippophae rhamnoides L.) in prevention and treatment of cardiovascular disease. Front. Cardiovasc. Med. 2024.

  6. Olas B. Sea buckthorn as a source of bioactive compounds in cardiovascular health. Food and Chemical Toxicology. 2016.

  7. Ried K. Garlic lowers blood pressure in hypertensive individuals: A systematic review and meta-analysis. BMC Cardiovascular Disorders. 2020.

  8. Ried K, et al. Effect of garlic on serum lipids: Updated meta-analysis. Nutrition Reviews. 2013.

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